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A unique family of Mrr-like modification-dependent restriction endonucleases

Mrr superfamily of homologous genes in microbial genomes restricts modified DNA in vivo. However, their biochemical properties in vitro have remained obscure. Here, we report the experimental characterization of MspJI, a remote homolog of Escherichia coli’s Mrr and show it is a DNA modification-depe...

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Detalles Bibliográficos
Autores principales: Zheng, Yu, Cohen-Karni, Devora, Xu, Derrick, Chin, Hang Gyeong, Wilson, Geoffrey, Pradhan, Sriharsa, Roberts, Richard J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938202/
https://www.ncbi.nlm.nih.gov/pubmed/20444879
http://dx.doi.org/10.1093/nar/gkq327