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Road blocks on paleogenomes—polymerase extension profiling reveals the frequency of blocking lesions in ancient DNA
Although the last few years have seen great progress in DNA sequence retrieval from fossil specimens, some of the characteristics of ancient DNA remain poorly understood. This is particularly true for blocking lesions, i.e. chemical alterations that cannot be bypassed by DNA polymerases and thus pre...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938203/ https://www.ncbi.nlm.nih.gov/pubmed/20587499 http://dx.doi.org/10.1093/nar/gkq572 |