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Yeast targets for mRNA methylation

N(6)-Methyladenosine (m(6)A) is a modified base present in the mRNA of all higher eukaryotes and in Saccharomyces cerevisiae, where there is an increase in m(6)A levels during sporulation. The methyltransferase, Ime4, is responsible for this modification and has a role in the initiation of meiosis....

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Detalles Bibliográficos
Autores principales: Bodi, Zsuzsanna, Button, James D., Grierson, Donald, Fray, Rupert G.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938207/
https://www.ncbi.nlm.nih.gov/pubmed/20421205
http://dx.doi.org/10.1093/nar/gkq266