Cargando…

An extended set of PRDM1/BLIMP1 target genes links binding motif type to dynamic repression

The transcriptional repressor B lymphocyte-induced maturation protein-1 (BLIMP1) regulates gene expression and cell fate. The DNA motif bound by BLIMP1 in vitro overlaps with that of interferon regulatory factors (IRFs), which respond to inflammatory/immune signals. At such sites, BLIMP1 and IRFs ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Doody, Gina M., Care, Matthew A., Burgoyne, Nicholas J., Bradford, James R., Bota, Maria, Bonifer, Constanze, Westhead, David R., Tooze, Reuben M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938208/
https://www.ncbi.nlm.nih.gov/pubmed/20421211
http://dx.doi.org/10.1093/nar/gkq268