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ANO1 amplification and expression in HNSCC with a high propensity for future distant metastasis and its functions in HNSCC cell lines

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is associated with poor survival. To identify prognostic and diagnostic markers and therapeutic targets, we studied ANO1, a recently identified calcium-activated chloride channel (CaCC). METHODS: High-resolution genomic and transcriptomic mic...

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Detalles Bibliográficos
Autores principales: Ayoub, C, Wasylyk, C, Li, Y, Thomas, E, Marisa, L, Robé, A, Roux, M, Abecassis, J, de Reyniès, A, Wasylyk, B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938263/
https://www.ncbi.nlm.nih.gov/pubmed/20664600
http://dx.doi.org/10.1038/sj.bjc.6605823