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Epigenetic Drugs Can Stimulate Metastasis through Enhanced Expression of the Pro-Metastatic Ezrin Gene

Ezrin has been reported to be upregulated in many tumors and to participate in metastatic progression. No study has addressed epigenetic modification in the regulation of Ezrin gene expression, the importance of which is unknown. Here, we report that highly metastatic rhabdomyosarcoma (RMS) cells wi...

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Detalles Bibliográficos
Autores principales: Yu, Yanlin, Zeng, Pingyao, Xiong, Jingbo, Liu, Ziyang, Berger, Shelley L., Merlino, Glenn
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938331/
https://www.ncbi.nlm.nih.gov/pubmed/20856924
http://dx.doi.org/10.1371/journal.pone.0012710