Interaction of the TNFR-Receptor Associated Factor TRAF1 with I-Kappa B Kinase-2 and TRAF2 Indicates a Regulatory Function for NF-Kappa B Signaling

BACKGROUND: I-kappa B kinase 2 (IKK2 or IKK-beta) is one of the most crucial signaling kinases for activation of NF-kappa B, a transcription factor that is important for inflammation, cell survival and differentiation. Since many NF-kappa B activating pathways converge at the level of IKK2, molecula...

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Detalles Bibliográficos
Autores principales: Sughra, Kalsoom, Birbach, Andreas, de Martin, Rainer, Schmid, Johannes A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938345/
https://www.ncbi.nlm.nih.gov/pubmed/20856938
http://dx.doi.org/10.1371/journal.pone.0012683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938345/
https://www.ncbi.nlm.nih.gov/pubmed/20856938
http://dx.doi.org/10.1371/journal.pone.0012683

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