Thymic Alterations in GM2 Gangliosidoses Model Mice

BACKGROUND: Sandhoff disease is a lysosomal storage disorder characterized by the absence of β-hexosaminidase and storage of GM2 ganglioside and related glycolipids. We have previously found that the progressive neurologic disease induced in Hexb (−/−) mice, an animal model for Sandhoff disease, is...

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Detalles Bibliográficos
Autores principales: Kanzaki, Seiichi, Yamaguchi, Akira, Yamaguchi, Kayoko, Kojima, Yoshitsugu, Suzuki, Kyoko, Koumitsu, Noriko, Nagashima, Yoji, Nagahama, Kiyotaka, Ehara, Michiko, Hirayasu, Yoshio, Ryo, Akihide, Aoki, Ichiro, Yamanaka, Shoji
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938369/
https://www.ncbi.nlm.nih.gov/pubmed/20856892
http://dx.doi.org/10.1371/journal.pone.0012105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938369/
https://www.ncbi.nlm.nih.gov/pubmed/20856892
http://dx.doi.org/10.1371/journal.pone.0012105

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