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Proteasome Nuclear Import Mediated by Arc3 Can Influence Efficient DNA Damage Repair and Mitosis in Schizosaccharomyces Pombe

Proteasomes must remove regulatory molecules and abnormal proteins throughout the cell, but how proteasomes can do so efficiently remains unclear. We have isolated a subunit of the Arp2/3 complex, Arc3, which binds proteasomes. When overexpressed, Arc3 rescues phenotypes associated with proteasome d...

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Detalles Bibliográficos
Autores principales: Cabrera, Rodrigo, Sha, Zhe, Vadakkan, Tegy J., Otero, Joel, Kriegenburg, Franziska, Hartmann-Petersen, Rasmus, Dickinson, Mary E., Chang, Eric C.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938379/
https://www.ncbi.nlm.nih.gov/pubmed/20668161
http://dx.doi.org/10.1091/mbc.E10-06-0506