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The Roles of Cyclin A2, B1, and B2 in Early and Late Mitotic Events

Here we have used siRNAs and time-lapse epifluorescence microscopy to examine the roles of various candidate mitotic cyclins in chromatin condensation in HeLa cells. Knocking down cyclin A2 resulted in a substantial (∼7 h) delay in chromatin condensation and histone H3 phosphorylation, and expressin...

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Detalles Bibliográficos
Autores principales: Gong, Delquin, Ferrell, James E.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938381/
https://www.ncbi.nlm.nih.gov/pubmed/20660152
http://dx.doi.org/10.1091/mbc.E10-05-0393