A Phosphatidic Acid Binding/Nuclear Localization Motif Determines Lipin1 Function in Lipid Metabolism and Adipogenesis

Lipins are phosphatidic acid phosphatases with a pivotal role in regulation of triglyceride and glycerophospholipid metabolism. Lipin1 is also an amplifier of PGC-1α, a nuclear coactivator of PPAR-α responsive gene transcription. Lipins do not contain recognized membrane-association domains, but int...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Hongmei, Federico, Lorenzo, Huang, Huiyan, Sunkara, Manjula, Drennan, Tracy, Frohman, Michael A., Smyth, Susan S., Morris, Andrew J.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938383/
https://www.ncbi.nlm.nih.gov/pubmed/20660155
http://dx.doi.org/10.1091/mbc.E10-01-0073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938383/
https://www.ncbi.nlm.nih.gov/pubmed/20660155
http://dx.doi.org/10.1091/mbc.E10-01-0073

Ejemplares similares