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A Phosphatidic Acid Binding/Nuclear Localization Motif Determines Lipin1 Function in Lipid Metabolism and Adipogenesis

Lipins are phosphatidic acid phosphatases with a pivotal role in regulation of triglyceride and glycerophospholipid metabolism. Lipin1 is also an amplifier of PGC-1α, a nuclear coactivator of PPAR-α responsive gene transcription. Lipins do not contain recognized membrane-association domains, but int...

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Detalles Bibliográficos
Autores principales:	Ren, Hongmei, Federico, Lorenzo, Huang, Huiyan, Sunkara, Manjula, Drennan, Tracy, Frohman, Michael A., Smyth, Susan S., Morris, Andrew J.
Formato:	Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2010
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938383/ https://www.ncbi.nlm.nih.gov/pubmed/20660155 http://dx.doi.org/10.1091/mbc.E10-01-0073

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