Phosphorylation of eIF2α at Serine 51 Is an Important Determinant of Cell Survival and Adaptation to Glucose Deficiency

Various forms of stress induce pathways that converge on the phosphorylation of the alpha (α) subunit of eukaryotic translation initiation factor eIF2 at serine 51 (S51), a modification that results in a global inhibition of protein synthesis. In many cases eIF2α phosphorylation is a biological resp...

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Detalles Bibliográficos
Autores principales: Muaddi, Hala, Majumder, Mithu, Peidis, Philippos, Papadakis, Andreas I., Holcik, Martin, Scheuner, Donalyn, Kaufman, Randal J., Hatzoglou, Maria, Koromilas, Antonis E.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938387/
https://www.ncbi.nlm.nih.gov/pubmed/20660158
http://dx.doi.org/10.1091/mbc.E10-01-0023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938387/
https://www.ncbi.nlm.nih.gov/pubmed/20660158
http://dx.doi.org/10.1091/mbc.E10-01-0023

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