The BNIP-2 and Cdc42GAP Homology (BCH) Domain of p50RhoGAP/Cdc42GAP Sequesters RhoA from Inactivation by the Adjacent GTPase-activating Protein Domain

The BNIP-2 and Cdc42GAP homology (BCH) domain is a novel regulator for Rho GTPases, but its impact on p50-Rho GTPase-activating protein (p50RhoGAP or Cdc42GAP) in cells remains elusive. Here we show that deletion of the BCH domain from p50RhoGAP enhanced its GAP activity and caused drastic cell roun...

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Detalles Bibliográficos
Autores principales: Zhou, Yi Ting, Chew, Li Li, Lin, Sheng-cai, Low, Boon Chuan
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938388/
https://www.ncbi.nlm.nih.gov/pubmed/20660160
http://dx.doi.org/10.1091/mbc.E09-05-0408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938388/
https://www.ncbi.nlm.nih.gov/pubmed/20660160
http://dx.doi.org/10.1091/mbc.E09-05-0408

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