Cargando…

Hypoxia-inducible Factor-1 Activation in Nonhypoxic Conditions: The Essential Role of Mitochondrial-derived Reactive Oxygen Species

Hypoxia-inducible factor-1 (HIF-1) is a key transcription factor for responses to low oxygen. Different nonhypoxic stimuli, including hormones and growth factors, are also important HIF-1 activators in the vasculature. Angiotensin II (Ang II), the main effecter hormone in the renin-angiotensin syste...

Descripción completa

Detalles Bibliográficos
Autores principales: Patten, David A., Lafleur, Véronique N., Robitaille, Geneviève A., Chan, Denise A., Giaccia, Amato J., Richard, Darren E.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938389/
https://www.ncbi.nlm.nih.gov/pubmed/20660157
http://dx.doi.org/10.1091/mbc.E10-01-0025