Prospects for the Use of Artificial Chromosomes and Minichromosome-Like Episomes in Gene Therapy

Artificial chromosomes and minichromosome-like episomes are large DNA molecules capable of containing whole genomic loci, and be maintained as nonintegrating, replicating molecules in proliferating human somatic cells. Authentic human artificial chromosomes are very difficult to engineer because of...

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Detalles Bibliográficos
Autores principales: Pérez-Luz, Sara, Díaz-Nido, Javier
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938438/
https://www.ncbi.nlm.nih.gov/pubmed/20862363
http://dx.doi.org/10.1155/2010/642804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938438/
https://www.ncbi.nlm.nih.gov/pubmed/20862363
http://dx.doi.org/10.1155/2010/642804

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