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Locking Src/Abl Tyrosine Kinase Activities Regulate Cell Differentiation and Invasion of Human Cervical Cancer Cells Expressing E6/E7 Oncoproteins of High-Risk HPV

In this study, we compared the effects of SKI-606 with Iressa, Src/Abl and EGF-R kinase inhibitors, respectively, on selected parameters in HeLa and SiHa cervical cancer cell lines, which express E6/E7 oncoproteins of high-risk HPV types 18 and 16, respectively. Our results show that SKI-606 and Ire...

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Detalles Bibliográficos
Autores principales: Yasmeen, Amber, Alachkar, Amal, Dekhil, Hafedh, Gambacorti-Passerini, Carlo, Al Moustafa, Ala-Eddin
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938462/
https://www.ncbi.nlm.nih.gov/pubmed/20862378
http://dx.doi.org/10.1155/2010/530130