A Proteomic Screen for Nucleolar SUMO Targets Shows SUMOylation Modulates the Function of Nop5/Nop58

Posttranslational SUMO modification is an important mechanism of regulating protein function, especially in the cell nucleus. The nucleolus is the subnuclear organelle responsible for rRNA synthesis, processing, and assembly of the large and small ribosome subunits. Here, we have used SILAC-based qu...

Descripción completa

Detalles Bibliográficos
Autores principales: Westman, Belinda J., Verheggen, Céline, Hutten, Saskia, Lam, Yun Wah, Bertrand, Edouard, Lamond, Angus I.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938476/
https://www.ncbi.nlm.nih.gov/pubmed/20797632
http://dx.doi.org/10.1016/j.molcel.2010.07.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938476/
https://www.ncbi.nlm.nih.gov/pubmed/20797632
http://dx.doi.org/10.1016/j.molcel.2010.07.025

Ejemplares similares