Cargando…

Spatial working memory deficits in GluA1 AMPA receptor subunit knockout mice reflect impaired short-term habituation: Evidence for Wagner's dual-process memory model

Genetically modified mice, lacking the GluA1 AMPA receptor subunit, are impaired on spatial working memory tasks, but display normal acquisition of spatial reference memory tasks. One explanation for this dissociation is that working memory, win-shift performance engages a GluA1-dependent, non-assoc...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanderson, David J., McHugh, Stephen B., Good, Mark A., Sprengel, Rolf, Seeburg, Peter H., Rawlins, J. Nicholas P., Bannerman, David M.
Formato: Texto
Lenguaje:English
Publicado: Pergamon Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938569/
https://www.ncbi.nlm.nih.gov/pubmed/20350557
http://dx.doi.org/10.1016/j.neuropsychologia.2010.03.018