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How Can Hydrophobic Association Be Enthalpy Driven?
Hydrophobic association is often recognized as being driven by favorable entropic contributions. Here, using explicit solvent molecular dynamics simulations we investigate binding in a model hydrophobic receptor−ligand system which appears, instead, to be driven by enthalpy and opposed by entropy. W...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938831/ https://www.ncbi.nlm.nih.gov/pubmed/20844599 http://dx.doi.org/10.1021/ct1003077 |