Synergistic action of RNA polymerases in overcoming the nucleosomal barrier

During gene expression, RNA polymerase (RNAP) encounters a major barrier at a nucleosome and yet must access the nucleosomal DNA. In vivo evidence suggests that multiple RNAPs might increase transcription efficiency through nucleosomes. Here we have quantitatively investigated this hypothesis using...

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Detalles Bibliográficos
Autores principales: Jin, Jing, Bai, Lu, Johnson, Daniel S., Fulbright, Robert M., Kireeva, Maria L., Kashlev, Mikhail, Wang, Michelle D.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938954/
https://www.ncbi.nlm.nih.gov/pubmed/20453861
http://dx.doi.org/10.1038/nsmb.1798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938954/
https://www.ncbi.nlm.nih.gov/pubmed/20453861
http://dx.doi.org/10.1038/nsmb.1798

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