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Synergistic action of RNA polymerases in overcoming the nucleosomal barrier
During gene expression, RNA polymerase (RNAP) encounters a major barrier at a nucleosome and yet must access the nucleosomal DNA. In vivo evidence suggests that multiple RNAPs might increase transcription efficiency through nucleosomes. Here we have quantitatively investigated this hypothesis using...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938954/ https://www.ncbi.nlm.nih.gov/pubmed/20453861 http://dx.doi.org/10.1038/nsmb.1798 |