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The Goldilocks Model for TCR—Too Much Attraction Might Not Be Best for Vaccine Design

Recent research on T cell-antigen interactions suggests that tighter binding is not always better at eliciting an effective immune response.

Detalles Bibliográficos
Autores principales: Slansky, Jill E., Jordan, Kimberly R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939021/
https://www.ncbi.nlm.nih.gov/pubmed/20856901
http://dx.doi.org/10.1371/journal.pbio.1000482