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The Goldilocks Model for TCR—Too Much Attraction Might Not Be Best for Vaccine Design
Recent research on T cell-antigen interactions suggests that tighter binding is not always better at eliciting an effective immune response.
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939021/ https://www.ncbi.nlm.nih.gov/pubmed/20856901 http://dx.doi.org/10.1371/journal.pbio.1000482 |
| _version_ | 1782186694397657088 |
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| author | Slansky, Jill E. Jordan, Kimberly R. |
| author_facet | Slansky, Jill E. Jordan, Kimberly R. |
| author_sort | Slansky, Jill E. |
| collection | PubMed |
| description | Recent research on T cell-antigen interactions suggests that tighter binding is not always better at eliciting an effective immune response. |
| format | Text |
| id | pubmed-2939021 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2010 |
| publisher | Public Library of Science |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-29390212010-09-20 The Goldilocks Model for TCR—Too Much Attraction Might Not Be Best for Vaccine Design Slansky, Jill E. Jordan, Kimberly R. PLoS Biol Primer Recent research on T cell-antigen interactions suggests that tighter binding is not always better at eliciting an effective immune response. Public Library of Science 2010-09-14 /pmc/articles/PMC2939021/ /pubmed/20856901 http://dx.doi.org/10.1371/journal.pbio.1000482 Text en Slansky, Jordan. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
| spellingShingle | Primer Slansky, Jill E. Jordan, Kimberly R. The Goldilocks Model for TCR—Too Much Attraction Might Not Be Best for Vaccine Design |
| title | The Goldilocks Model for TCR—Too Much Attraction Might Not Be Best for Vaccine Design |
| title_full | The Goldilocks Model for TCR—Too Much Attraction Might Not Be Best for Vaccine Design |
| title_fullStr | The Goldilocks Model for TCR—Too Much Attraction Might Not Be Best for Vaccine Design |
| title_full_unstemmed | The Goldilocks Model for TCR—Too Much Attraction Might Not Be Best for Vaccine Design |
| title_short | The Goldilocks Model for TCR—Too Much Attraction Might Not Be Best for Vaccine Design |
| title_sort | goldilocks model for tcr—too much attraction might not be best for vaccine design |
| topic | Primer |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939021/ https://www.ncbi.nlm.nih.gov/pubmed/20856901 http://dx.doi.org/10.1371/journal.pbio.1000482 |
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