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Attenuated T Cell Responses to a High-Potency Ligand In Vivo

αβ T cell receptor (TCR) recognition of foreign peptides bound to major histocompatibility complex (pMHC) molecules on the surface of antigen presenting cells is a key event in the initiation of adaptive cellular immunity. In vitro, high-affinity binding and/or long-lived interactions between TCRs a...

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Detalles Bibliográficos
Autores principales: Corse, Emily, Gottschalk, Rachel A., Krogsgaard, Michelle, Allison, James P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939023/
https://www.ncbi.nlm.nih.gov/pubmed/20856903
http://dx.doi.org/10.1371/journal.pbio.1000481