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Attenuated T Cell Responses to a High-Potency Ligand In Vivo
αβ T cell receptor (TCR) recognition of foreign peptides bound to major histocompatibility complex (pMHC) molecules on the surface of antigen presenting cells is a key event in the initiation of adaptive cellular immunity. In vitro, high-affinity binding and/or long-lived interactions between TCRs a...
Autores principales: | Corse, Emily, Gottschalk, Rachel A., Krogsgaard, Michelle, Allison, James P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939023/ https://www.ncbi.nlm.nih.gov/pubmed/20856903 http://dx.doi.org/10.1371/journal.pbio.1000481 |
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