MnSOD Upregulation Induces Autophagic Programmed Cell Death in Senescent Keratinocytes

Senescence is a state of growth arrest resulting mainly from telomere attrition and oxidative stress. It ultimately leads to cell death. We have previously shown that, in keratinocytes, senescence is induced by NF-kappaB activation, MnSOD upregulation and H(2)O(2) overproduction. We have also shown...

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Detalles Bibliográficos
Autores principales: Deruy, Emeric, Gosselin, Karo, Vercamer, Chantal, Martien, Sébastien, Bouali, Fatima, Slomianny, Christian, Bertout, Julie, Bernard, David, Pourtier, Albin, Abbadie, Corinne
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939051/
https://www.ncbi.nlm.nih.gov/pubmed/20856861
http://dx.doi.org/10.1371/journal.pone.0012712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939051/
https://www.ncbi.nlm.nih.gov/pubmed/20856861
http://dx.doi.org/10.1371/journal.pone.0012712

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