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MnSOD Upregulation Induces Autophagic Programmed Cell Death in Senescent Keratinocytes
Senescence is a state of growth arrest resulting mainly from telomere attrition and oxidative stress. It ultimately leads to cell death. We have previously shown that, in keratinocytes, senescence is induced by NF-kappaB activation, MnSOD upregulation and H(2)O(2) overproduction. We have also shown...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939051/ https://www.ncbi.nlm.nih.gov/pubmed/20856861 http://dx.doi.org/10.1371/journal.pone.0012712 |