Cargando…

Role of CD45 Signaling Pathway in Galactoxylomannan-Induced T Cell Damage

Previously, we reported that Galactoxylomannan (GalXM) activates the extrinsic and intrinsic apoptotic pathways through an interaction with the glycoreceptors on T cells. In this study we establish the role of the glycoreceptor CD45 in GalXM-induced T cell apoptosis, using CD45(+/+) and CD45(−/−) ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Pericolini, Eva, Gabrielli, Elena, Bistoni, Giovanni, Cenci, Elio, Perito, Stefano, Chow, Siu-Kei, Riuzzi, Francesca, Donato, Rosario, Casadevall, Arturo, Vecchiarelli, Anna
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939064/
https://www.ncbi.nlm.nih.gov/pubmed/20856869
http://dx.doi.org/10.1371/journal.pone.0012720