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Prohibitins Are Required for Cancer Cell Proliferation and Adhesion

Prohibitin 1 (PHB1) is a highly conserved protein that together with its homologue prohibitin 2 (PHB2) mainly localizes to the inner mitochondrial membrane. Although it was originally identified by its ability to inhibit G1/S progression in human fibroblasts, its role as tumor suppressor is debated....

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Detalles Bibliográficos
Autores principales: Sievers, Claudia, Billig, Gwendolyn, Gottschalk, Kathleen, Rudel, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939069/
https://www.ncbi.nlm.nih.gov/pubmed/20856874
http://dx.doi.org/10.1371/journal.pone.0012735