The Crystal Structure of Toxoplasma gondii Pyruvate Kinase 1

BACKGROUND: Pyruvate kinase (PK), which catalyzes the final step in glycolysis converting phosphoenolpyruvate to pyruvate, is a central metabolic regulator in most organisms. Consequently PK represents an attractive therapeutic target in cancer and human pathogens, like Apicomplexans. The phylum Apl...

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Detalles Bibliográficos
Autores principales: Bakszt, Rebecca, Wernimont, Amy, Allali-Hassani, Abdellah, Mok, Man Wai, Hills, Tanya, Hui, Raymond, Pizarro, Juan C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939071/
https://www.ncbi.nlm.nih.gov/pubmed/20856875
http://dx.doi.org/10.1371/journal.pone.0012736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939071/
https://www.ncbi.nlm.nih.gov/pubmed/20856875
http://dx.doi.org/10.1371/journal.pone.0012736

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