Ty1 integrase overexpression leads to integration of non-Ty1 DNA fragments into the genome of Saccharomyces cerevisiae

The integrase of the Saccharomyces cerevisiae retrotransposon Ty1 integrates Ty1 cDNA into genomic DNA likely via a transesterification reaction. Little is known about the mechanisms ensuring that integrase does not integrate non-Ty DNA fragments. In an effort to elucidate the conditions under which...

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Detalles Bibliográficos
Autores principales: Friedl, Anna A., Kiechle, Markus, Maxeiner, Horst G., Schiestl, Robert H., Eckardt-Schupp, Friederike
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939329/
https://www.ncbi.nlm.nih.gov/pubmed/20677012
http://dx.doi.org/10.1007/s00438-010-0561-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939329/
https://www.ncbi.nlm.nih.gov/pubmed/20677012
http://dx.doi.org/10.1007/s00438-010-0561-4

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