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Expression of Hepatitis B Virus X Protein in Hepatocytes Suppresses CD8(+) T Cell Activity

BACKGROUND: CD8(+) T cells contribute to the clearance of Hepatitis B virus (HBV) infection and an insufficient CD8(+) T cell response may be one of the major factors leading to chronic HBV infection. Since the HBx antigen of HBV can up-regulate cellular expression of several immunomodulatory molecu...

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Detalles Bibliográficos
Autores principales: Lee, Mi Jin, Jin, Young-hee, Kim, Kyongmin, Choi, Yangkyu, Kim, Hyoung-Chin, Park, Sun
Formato: Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939357/
https://www.ncbi.nlm.nih.gov/pubmed/20844737
http://dx.doi.org/10.4110/in.2010.10.4.126