IL-2 Mediates CD4(+) T Cell Help in the Breakdown of Memory-Like CD8(+) T Cell Tolerance under Lymphopenic Conditions

BACKGROUND: Lymphopenia results in the proliferation and differentiation of naïve T cells into memory-like cells in the apparent absence of antigenic stimulation. This response, at least in part due to a greater availability of cytokines, is thought to promote anti-self responses. Although potential...

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Detalles Bibliográficos
Autores principales: Le Saout, Cécile, Villard, Marine, Cabasse, Clémence, Jacquet, Chantal, Taylor, Naomi, Hernandez, Javier
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939396/
https://www.ncbi.nlm.nih.gov/pubmed/20856822
http://dx.doi.org/10.1371/journal.pone.0012659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939396/
https://www.ncbi.nlm.nih.gov/pubmed/20856822
http://dx.doi.org/10.1371/journal.pone.0012659

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