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IL-2 Mediates CD4(+) T Cell Help in the Breakdown of Memory-Like CD8(+) T Cell Tolerance under Lymphopenic Conditions
BACKGROUND: Lymphopenia results in the proliferation and differentiation of naïve T cells into memory-like cells in the apparent absence of antigenic stimulation. This response, at least in part due to a greater availability of cytokines, is thought to promote anti-self responses. Although potential...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939396/ https://www.ncbi.nlm.nih.gov/pubmed/20856822 http://dx.doi.org/10.1371/journal.pone.0012659 |