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SLC2A10 genetic polymorphism predicts development of peripheral arterial disease in patients with type 2 diabetes. SLC2A10 and PAD in type 2 diabetes

BACKGROUND: Recent data indicate that loss-of-function mutation in the gene encoding the facilitative glucose transporter GLUT10 (SLC2A10) causes arterial tortuosity syndrome via upregulation of the TGF-β pathway in the arterial wall, a mechanism possibly causing vascular changes in diabetes. METHOD...

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Detalles Bibliográficos
Autores principales: Jiang, Yi-Der, Chang, Yi-Cheng, Chiu, Yen-Feng, Chang, Tien-Jyun, Li, Hung-Yuan, Lin, Wen-Hsing, Yuan, Hsiang-Yu, Chen, Yuan-Tsong, Chuang, Lee-Ming
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939510/
https://www.ncbi.nlm.nih.gov/pubmed/20735855
http://dx.doi.org/10.1186/1471-2350-11-126