Relative quantification of PIK3CA gene expression level in fine-needle aspiration biopsy thyroid specimens collected from patients with papillary thyroid carcinoma and non-toxic goitre by real-time RT-PCR

BACKGROUND: Recent studies have shown that the phosphatidylinositol 3-kinase (PI3K) signaling pathway is important regulator of many cellular events, including apoptosis, proliferation and motility. PI3K pathway alterations (PIK3CA gene mutations and/or amplification) have been observed in various h...

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Detalles Bibliográficos
Autores principales: Wojciechowska-Durczyńska, Katarzyna, Krawczyk-Rusiecka, Kinga, Cyniak-Magierska, Anna, Zygmunt, Arkadiusz, Gałecka, Elżbieta, Lewiński, Andrzej
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939511/
https://www.ncbi.nlm.nih.gov/pubmed/20804548
http://dx.doi.org/10.1186/1756-6614-3-5