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Molecular analysis of ex-vivo CD133+ GBM cells revealed a common invasive and angiogenic profile but different proliferative signatures among high grade gliomas

BACKGROUND: Gliomas are the most common type of primary brain tumours, and in this group glioblastomas (GBMs) are the higher-grade gliomas with fast progression and unfortunate prognosis. Two major aspects of glioma biology that contributes to its awful prognosis are the formation of new blood vesse...

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Detalles Bibliográficos
Autores principales: Garcia, Juan L, Perez-Caro, Maria, Gomez-Moreta, Juan A, Gonzalez, Francisco, Ortiz, Javier, Blanco, Oscar, Sancho, Magdalena, Hernandez-Rivas, Jesus M, Gonzalez-Sarmiento, Rogelio, Sanchez-Martin, Manuel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939550/
https://www.ncbi.nlm.nih.gov/pubmed/20735813
http://dx.doi.org/10.1186/1471-2407-10-454