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Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival

BACKGROUND: Musashi1 (Msi1) is a conserved RNA-binding protein that regulates the Notch and Wnt pathways, and serves as a stem cell marker in the breast and other tissues. It is unknown how Msi1 relates to other breast cancer markers, whether it denotes tumor initiating cells (TICs), and how it affe...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Yang, Penalva, Luiz OF, Yuan, Hongyan, Linnoila, R Ilona, Lu, Jiachun, Okano, Hideyuki, Glazer, Robert I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939568/
https://www.ncbi.nlm.nih.gov/pubmed/20727204
http://dx.doi.org/10.1186/1476-4598-9-221