The NRF2-mediated oxidative stress response pathway is associated with tumor cell resistance to arsenic trioxide across the NCI-60 panel

BACKGROUND: Drinking water contaminated with inorganic arsenic is associated with increased risk for different types of cancer. Paradoxically, arsenic trioxide can also be used to induce remission in patients with acute promyelocytic leukemia (APL) with a success rate of approximately 80%. A compreh...

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Detalles Bibliográficos
Autores principales: Liu, Qian, Zhang, Hao, Smeester, Lisa, Zou, Fei, Kesic, Matt, Jaspers, Ilona, Pi, Jingbo, Fry, Rebecca C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939609/
https://www.ncbi.nlm.nih.gov/pubmed/20707922
http://dx.doi.org/10.1186/1755-8794-3-37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939609/
https://www.ncbi.nlm.nih.gov/pubmed/20707922
http://dx.doi.org/10.1186/1755-8794-3-37

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