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Forward-time simulation of realistic samples for genome-wide association studies

BACKGROUND: Forward-time simulations have unique advantages in power and flexibility for the simulation of genetic samples of complex human diseases because they can closely mimic the evolution of human populations carrying these diseases. However, a number of methodological and computational constr...

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Detalles Bibliográficos
Autores principales: Peng, Bo, Amos, Christopher I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939614/
https://www.ncbi.nlm.nih.gov/pubmed/20809983
http://dx.doi.org/10.1186/1471-2105-11-442