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Upregulation of synaptotagmin IV inhibits transmitter release in PC12 cells with targeted synaptotagmin I knockdown
BACKGROUND: The function of synaptotagmins (syt) in Ca(2+)-dependent transmitter release has been attributed primarily to Ca(2+)-dependent isoforms such as syt I. Recently, syt IV, an inducible Ca(2+)-independent isoform has been implicated in transmitter release. We postulated that the effects of s...
Autores principales: | Moore-Dotson, Johnnie M, Papke, Jason B, Harkins, Amy B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939654/ https://www.ncbi.nlm.nih.gov/pubmed/20735850 http://dx.doi.org/10.1186/1471-2202-11-104 |
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