Mechanistic modelling of dynamic MRI data predicts that tumour heterogeneity decreases therapeutic response

BACKGROUND: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) contains crucial information about tumour heterogeneity and the transport limitations that reduce drug efficacy. Mathematical modelling of drug delivery and cellular responsiveness based on underutilised DCE-MRI data has the...

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Detalles Bibliográficos
Autores principales: Venkatasubramanian, R, Arenas, R B, Henson, M A, Forbes, N S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939778/
https://www.ncbi.nlm.nih.gov/pubmed/20628390
http://dx.doi.org/10.1038/sj.bjc.6605773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939778/
https://www.ncbi.nlm.nih.gov/pubmed/20628390
http://dx.doi.org/10.1038/sj.bjc.6605773

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