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Cardiovascular Risk Associated with Interactions among Polymorphisms in Genes from the Renin-Angiotensin, Bradykinin, and Fibrinolytic Systems

BACKGROUND: Vascular fibrinolytic balance is maintained primarily by interplay of tissue plasminogen activator (t-PA) and plasminogen activator inhibitor type 1 (PAI-1). Previous research has shown that polymorphisms in genes from the renin-angiotensin (RA), bradykinin, and fibrinolytic systems affe...

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Detalles Bibliográficos
Autores principales: Bentley, John P., Asselbergs, Folkert W., Coffey, Christopher S., Hebert, Patricia R., Moore, Jason H., Hillege, Hans L., van Gilst, Wiek H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939877/
https://www.ncbi.nlm.nih.gov/pubmed/20856803
http://dx.doi.org/10.1371/journal.pone.0012757