Diclofenac Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer by Modulation of VEGF Levels and Arginase Activity

BACKGROUND: Diclofenac is one of the oldest anti-inflammatory drugs in use. In addition to its inhibition of cyclooxygenases (COX), diclofenac potently inhibits phospholipase A(2) (PLA(2)), thus yielding a broad anti-inflammatory effect. Since inflammation is an important factor in the development o...

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Detalles Bibliográficos
Autores principales: Mayorek, Nina, Naftali-Shani, Nili, Grunewald, Myriam
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939880/
https://www.ncbi.nlm.nih.gov/pubmed/20856806
http://dx.doi.org/10.1371/journal.pone.0012715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939880/
https://www.ncbi.nlm.nih.gov/pubmed/20856806
http://dx.doi.org/10.1371/journal.pone.0012715

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