Regulation of Thromboxane Receptor Signaling at Multiple Levels by Oxidative Stress-Induced Stabilization, Relocation and Enhanced Responsiveness

BACKGROUND: Thromboxane A(2) (TxA(2)) is a major, unstable arachidonic acid metabolite, and plays a key role in normal physiology and control of vascular tone. The human thromboxane receptor (TPβ), expressed in COS-7 cells, is located predominantly in the endoplasmic reticulum (ER). Brief hydrogen p...

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Detalles Bibliográficos
Autores principales: Ball, Stephen K., Field, Mark C., Tippins, John R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939892/
https://www.ncbi.nlm.nih.gov/pubmed/20856817
http://dx.doi.org/10.1371/journal.pone.0012798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939892/
https://www.ncbi.nlm.nih.gov/pubmed/20856817
http://dx.doi.org/10.1371/journal.pone.0012798

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