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Simvastatin and purine analogs have a synergic effect on apoptosis of chronic lymphocytic leukemia cells

Despite many therapeutic regimens introduced recently, chronic lymphocytic leukemia (CLL) is still an incurable disorder. Thus, there is an urgent need to discover novel, less toxic and more effective drugs for CLL patients. In this study, we attempted to assess simvastatin, widely used as a cholest...

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Detalles Bibliográficos
Autores principales: Podhorecka, Monika, Halicka, Dorota, Klimek, Piotr, Kowal, Malgorzata, Chocholska, Sylwia, Dmoszynska, Anna
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940031/
https://www.ncbi.nlm.nih.gov/pubmed/20499237
http://dx.doi.org/10.1007/s00277-010-0988-z