Approximate Bayesian feature selection on a large meta-dataset offers novel insights on factors that effect siRNA potency

Motivation: Short interfering RNA (siRNA)-induced RNA interference is an endogenous pathway in sequence-specific gene silencing. The potency of different siRNAs to inhibit a common target varies greatly and features affecting inhibition are of high current interest. The limited success in predicting...

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Detalles Bibliográficos
Autores principales: Klingelhoefer, Jochen W., Moutsianas, Loukas, Holmes, Chris
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940241/
https://www.ncbi.nlm.nih.gov/pubmed/19420052
http://dx.doi.org/10.1093/bioinformatics/btp284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940241/
https://www.ncbi.nlm.nih.gov/pubmed/19420052
http://dx.doi.org/10.1093/bioinformatics/btp284

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