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Approximate Bayesian feature selection on a large meta-dataset offers novel insights on factors that effect siRNA potency
Motivation: Short interfering RNA (siRNA)-induced RNA interference is an endogenous pathway in sequence-specific gene silencing. The potency of different siRNAs to inhibit a common target varies greatly and features affecting inhibition are of high current interest. The limited success in predicting...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940241/ https://www.ncbi.nlm.nih.gov/pubmed/19420052 http://dx.doi.org/10.1093/bioinformatics/btp284 |