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The Aryl hydrocarbon Receptor (AhR) interacts with c-Maf to promote the differentiation of IL-27-induced regulatory type 1 (T(R)1) cells
IL-10 producing regulatory type 1 (T(R)1) T cells are instrumental in the prevention of tissue inflammation, autoimmunity and graft-versus-host disease. The transcription factor c-Maf is essential for T(R)1 induction of IL-10, but the molecular mechanisms leading to the development of these cells re...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940320/ https://www.ncbi.nlm.nih.gov/pubmed/20676095 http://dx.doi.org/10.1038/ni.1912 |